EFFECTS OF FENTANYL ON INTRACRANIAL PRESSURE AND CEREBRAL PERFUSION PRESSURE DURING HYPOCAPNIA
نویسندگان
چکیده
منابع مشابه
The effects of droperidol and fentanyl on intracranial pressure and cerebral perfusion pressure in neurosurgical patients.
The effects of droperidol and fentanyl on the intracranial pressure (i.c.p.) and cerebral perfusion pressure (c.p.p.) were studied in eight anaesthetized normocapnic patients with intracranial space-occupying lesions. The infection of droperidol resulted in a small and not significant increase in i.c.p. from 24.0 to 27.2 mm Hg, while c.p.p. decreased from 75.9 mm Hg to 57.8 mm Hg, as a result o...
متن کاملEffect of etomidate on intracranial pressure and cerebral perfusion pressure.
Ten patients with intracranial lesions, anaesthetized with thiopentone and nitrous oxide (70%) in oxygen (30%) received etomidate 0.2 mg kg-1 i.v. Ventilation was controlled in each patient. Intracranial pressure (i.c.p.) and mean arterial pressure (m.a.p.) were recorded. I.c.p. decreased significantly in all patients (0.01 greater than P greater than 0.001). Although PaCO2 decreased during the...
متن کاملEffect of cerebral perfusion pressure on cerebral cortical microvascular shunting at high intracranial pressure in rats.
BACKGROUND AND PURPOSE Recently, we showed that decreasing cerebral perfusion pressure (CPP) from 70 mm Hg to 50 mm Hg and 30 mm Hg by increasing intracranial pressure (ICP) with a fluid reservoir induces a transition from capillary (CAP) to microvascular shunt (MVS) flow in the uninjured rat brain. This transition was associated with tissue hypoxia, increased blood-brain barrier (BBB) permeabi...
متن کاملCerebral perfusion pressure management of severe diffuse head injury: effect on brain compliance and intracranial pressure.
BACKGROUND Cerebral perfusion pressure management (CPPM) is an accepted modality of treatment of severe diffuse head injury (SDHI). However, CPPM has the potential to cause transcapillary exudation in the presence of a disrupted blood brain barrier and can lead to further increase of intracranial pressure (ICP) and worsening of compliance. AIMS This study attempts to evaluate the effect of bo...
متن کامل19 Management of Intracranial Pressure and Cerebral Perfusion
The treatment of traumatic brain injury is based on the conceptual distinction between primary and secondary injury. Primary injury comprises the immediate effects of impact. Secondary injury is due to factors other than the direct impact and may begin almost immediately or some time later. The distinction is of course, not so sharp. It is increasingly clear that the impact initiates a series o...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1978
ISSN: 0007-0912
DOI: 10.1093/bja/50.8.779